Responding to the reee guy, none of your arguments disprove that Dororo identifies as male. All you are saying is that trans people did not exist during that time (which is completely and utterly false.) It seems that people like you often say that since the term "transgender" has existed only for about a century, trans people did not exist beforehand. This is like saying gravity didn't exist before scientists discovered it. There have been documentations that describe findings of trans people in ancient Rome, Greece, America, and France (the first accounting of gender dysphoria.) Scientific consensus agrees that trans people have probably existed for as long as gender roles have, but you don't really seem to care about science and expert opinions all that much, so maybe I need to speak more to your "level."
The sad thing is that you are trying to have a discussion on Dororo's gender, yet you don't even understand what gender is. You conflate sex with gender, and then talk about intersex (which is not a gender, but a sex.) I have no idea why you brought up chromosomes either. It has nothing to do with someone's gender identity. Yes, people born as one sex will typically have a gender that aligns with that sex (such as a biological female identifying as a woman.) But gender is far more complex than you make it out to be. The scientific consensus is that gender is a spectrum. I don't know why you said "scientifically" when the scientific community disagrees with your "2 gender" notion. I advise you actually do some research before you make demonstrably false claims, but then again, we are talking on a discussion board on an anime wiki page (and you're most likely a young teenager who has only heard about gender through anti-SJW reactionaries on Youtube, soooo...)